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Prostate cancer is the most common cancer in American men. About 1 man in 7 will be diagnosed with prostate cancer during his lifetime. About 5 to 10 percent of all prostate cancers diagnosed are hereditary, meaning that an increased risk for the disease runs in the family. Family history is the strongest risk factor for prostate cancer.
Patients have an increased risk of developing this disease if they have:
• 2 or more close relatives who had prostate cancer diagnosed under the age of 55;
• 3 or more first degree relatives with prostate cancer at any age; or
• had a close relative diagnosed with aggressive prostate cancer and 2 or more cases of breast, ovarian and/or pancreatic cancer in close relatives
In the Hereditary Cancer Panel - Prostate Cancer, the following genes are analyzed: BRCA2 and TP53, including deletions and insertions.